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Professor of Psychology Department of Psychology
Area of Interest My research focuses on the neurobiology of learning and memory, with particular interest in neurochemical and pharmacological enhancement of memory. The laboratory is broadly based with interests ranging from cellular neurobiology to human neuropsychology, with a major effort directed at assessing age-related changes in brain function and in memory. Using in vivo microdialysis / HPLC in young and aged rodents, we assess release of acetylcholine and other neurotransmitters in the brain during learning and memory to evaluate changes in neural systems that participate in memory formation. Other experiments use pharmacological treatments to enhance memory functions in young and aged rodents and humans. Publications McNay, E.C. and Gold, P.E. (2001). Age-related differences in hippocampal extracellular fluid glucose concentration during behavioral testing and following systemic glucose administration. Journal of Gerontology: Biological Sciences, 56A, B66-B71. Gold, P.E., McIntyre, C., McNay, E., Stefani, M.R., and Korol, D.L. (2001). Neurochemical referees of dueling memory systems. In: Gold, P.E. and Greenough, W.T. (Eds.), Memory Consolidation: Essays in Honor of James L. McGaugh A Time to Remember. American Psychological Association Publishers, Washington, D.C. pp. 219-248. Men, D., McIntyre, C.K., McCarty, R. and Gold, P.E. (2001). Age-related changes in extracellular acetylcholine and norepinephrine levels in the rat hippocampus. Neurobiology of Aging, in press. Gold, P. E. (2001). Drug enhancement of memory in aged rodents and humans. In M. E. Carroll & J. B. Overmier (Eds.), Animal research and human health: Advancing human welfare through behavioral science (pp. 293-304). Washington, DC: American Psychological Association. McNay, E.C., McCarty, R.M. and Gold, P.E. (2001). Fluctuations in glucose concentration during behavioral testing: Dissociations both between brain areas and between brain and blood. Neurobiology of Learning and Memory, 75, 325-337. Keywords neuroscience, learning, memory, aging, pharmacology |
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2001 University of Illinois @ Urbana-Champaign
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Paul
E. Gold, Ph.D.